pharmacology of lisinopril
(lye SIH no pril)
Prinivil, Zestril
What is the most important information I should know about lisinopril?
• Do not take lisinopril if you are pregnant or planning a pregnancy pharmacology of lisinopril. Whenused during the second and third trimesters of pregnancy, lisinopril can causeinjury and even death to the developing fetus pharmacology of lisinopril. Notify your doctor immediatelyif you think you might be pregnant pharmacology of lisinopril.
• Lisinopril may increase the risk of dangerous allergic reactions pharmacology of lisinopril. Beforetaking lisinopril, tell your doctor if you have ever had an allergic reactionthat involved swelling of your lips, face, tongue, or throat or difficulty breathing pharmacology of lisinopril. Seek emergency medical attention if you develop any of these symptoms whiletaking lisinopril pharmacology of lisinopril.
• Heavy sweating, vomiting, diarrhea, or other causes of fluid loss maylead to very low blood pressure, dizziness, and fainting during therapy withlisinopril pharmacology of lisinopril. Maintain proper fluid intake to prevent dehydration and relatedside effects pharmacology of lisinopril.
What is lisinopril?
• Lisinopril is in a class of drugs called angiotensin-converting-enzyme(ACE) inhibitors pharmacology of lisinopril.
• Lisinopril is used to lower blood pressure, to treat congestive heartfailure, and to improve the survival rate after a heart attack pharmacology of lisinopril.
• Lisinopril may also be used for purposes other than those listed in thismedication guide pharmacology of lisinopril.
Who should not take lisinopril?
• Lisinopril may increase the risk of dangerous allergic reactions pharmacology of lisinopril. Beforetaking lisinopril, tell your doctor if you have ever had an allergic reactionthat involved swelling of your lips, face, tongue, or throat or difficulty breathing pharmacology of lisinopril. Seek emergency medical attention if you develop any of these symptoms whiletaking lisinopril pharmacology of lisinopril.
• Before taking lisinopril, tell your doctor if you
· have kidney disease;
· are on a salt-restricted diet or have high levels of potassium in yourblood;
· are taking salt substitutes, potassium supplements (e.g., K-Dur, Klor-Con),or potassium-sparing diuretics such as amiloride (Midamor), triamterene (Dyrenium,Dyazide, Maxzide), or spironolactone (Aldactone); or
· have diabetes pharmacology of lisinopril.
• You may not be able to take lisinopril, or you may require a dosage adjustmentor special monitoring during treatment if you have any of the conditions listedabove pharmacology of lisinopril.
• Lisinopril is in the FDA pregnancy category D pharmacology of lisinopril. This means that lisinoprilis known to harm an unborn baby pharmacology of lisinopril. When used during the second and third trimestersof pregnancy, lisinopril can cause injury and even death to the developing fetus.Donot take lisinopril if you are pregnant pharmacology of lisinopril.
• It is not known whether lisinopril passes into breast milk, and its effectson a nursing baby are not known pharmacology of lisinopril. Do not take lisinopril without first talkingto your doctor if you are breast-feeding a baby pharmacology of lisinopril.
How should I take lisinopril?
• Take lisinopril exactly as directed by your doctor pharmacology of lisinopril. If you do not understandthese directions, ask your pharmacist, nurse, or doctor to explain them to you pharmacology of lisinopril.
• Take each dose with a full glass of water pharmacology of lisinopril.
• Lisinopril can be taken with or without food pharmacology of lisinopril.
• Do not stop taking lisinopril without first talking to your doctor pharmacology of lisinopril. Ifyou stop taking this medication suddenly, your condition could become worse pharmacology of lisinopril.
• Store lisinopril at room temperature away from moisture and heat pharmacology of lisinopril.
What happens if I miss a dose?
• Take the missed dose as soon as you remember pharmacology of lisinopril. However, if it is almosttime for your next dose, skip the missed dose and take only your next regularlyscheduled dose pharmacology of lisinopril. Do not take a double dose of this medication pharmacology of lisinopril.
What happens if I overdose?
• Seek emergency medical attention pharmacology of lisinopril.
• Symptoms of a lisinopril overdose include extreme dizziness, weakness,fainting, and fatigue pharmacology of lisinopril.
What should I avoid while taking lisinopril?
• Use caution when driving, operating machinery, or performing other hazardousactivities pharmacology of lisinopril. Lisinopril may cause dizziness or drowsiness pharmacology of lisinopril. If you experiencedizziness or drowsiness, avoid these activities and notify your doctor pharmacology of lisinopril. Alsouse caution when rising from a sitting or lying position pharmacology of lisinopril.
• Use alcohol cautiously pharmacology of lisinopril. Alcohol may increase drowsiness and dizzinesswhile you are taking lisinopril pharmacology of lisinopril. Alcohol may further lower blood pressure andincrease drowsiness and dizziness when you are taking lisinopril pharmacology of lisinopril.
• Do not use salt substitutes or potassium supplements while taking lisinoprilexcept under the supervision of your doctor pharmacology of lisinopril.
• Heavy sweating, vomiting, diarrhea, or other causes of fluid loss maylead to very low blood pressure, dizziness, and fainting during therapy withlisinopril pharmacology of lisinopril. Maintain proper fluid intake to prevent dehydration and relatedside effects pharmacology of lisinopril.
What are the possible side effects of lisinopril?
• If you experience any of the following serious side effects, stop takinglisinopril and call your doctor immediately or seek emergency medical treatment:
· an allergic reaction (difficulty breathing; closing of your throat;swelling of your lips, tongue, or face; or hives);
· difficulty breathing;
· little or no urine;
· an irregular heartbeat or changes in your heartbeat;
· chest pain;
· severe dizziness or fainting; or
· signs of an infection including a sore throat or a fever pharmacology of lisinopril.
• Other, less serious side effects may be more likely to occur pharmacology of lisinopril. Continueto take lisinopril and talk to your doctor if you experience
· mild dizziness or lightheadedness;
· headache;
· unusual fatigue or weakness;
· dry, tickling cough;
· muscle cramps;
· numbness or tingling in the hands, feet, arms, or legs;
· nausea, vomiting, or diarrhea;
· a rash; or
· impotence pharmacology of lisinopril.
• Side effects other than those listed here may also occur pharmacology of lisinopril. Talk to yourdoctor about any side effect that seems unusual or that is especially bothersome pharmacology of lisinopril.
What other drugs will affect lisinopril?
• Before taking lisinopril, tell your doctor if you are taking any of thefollowing drugs:
· a potassium supplement such as K-Dur, Klor-Con, and others;
· salt substitutes that contain potassium;
· any of the diuretics (water pills) triamterene (Dyrenium, Maxzide,Dyazide), spironolactone (Aldactone), or amiloride (Midamor);
· any other diuretic (water pill) such as hydrochlorothiazide (HCTZ,HydroDiuril, others), furosemide (Lasix), bumetanide (Bumex), indapamide (Lozol),and others;
· lithium (Lithobid, Eskalith, others); or
· indomethacin (Indocin) pharmacology of lisinopril.
• You may not be able to take lisinopril, or you may require a dosage adjustmentor special monitoring during your treatment if you are taking any of the medicineslisted above pharmacology of lisinopril.
• Drugs other than those listed here may also interact with lisinoprilor affect your condition pharmacology of lisinopril. Talk to your doctor and pharmacist before taking anyprescription or over-the-counter medicines pharmacology of lisinopril.
Where can I get more information?
• Your pharmacist has additional information about lisinopril written forhealth professionals that you may read pharmacology of lisinopril.
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